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Results: 57
Number of items: 57
  • Open Access
    Rodenko, B., Wanner, M. J., Alkhaldi, A. A. M., Ebiloma, G. U., Barnes, R. L., Kaiser, M., Brun, R., McCulloch, R., Koomen, G. J., & de Koning, H. P. (2015). Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy. Antimicrobial Agents and Chemotherapy, 59(11), 6708-6716. https://doi.org/10.1128/AAC.00596-15
  • Rodenko, B., Al-Salabi, M. I., Teka, I. A., Ho, W., El-Sabbagh, N., Ali, J. A. M., Ibrahim, H. M. S., Wanner, M. J., Koomen, G. J., & de Koning, H. P. (2011). Synthesis of marine-derived 3-alkylpyridinium alkaloids with potent antiprotozoal activity. ACS Medicinal Chemistry Letters, 2(12), 901-906. https://doi.org/10.1021/ml200160k
  • Open Access
    Koch, M. (2011). Novel antagonists for the human adenosine A2A and A3 receptor via purine nitration: synthesis and biological evaluation of C2-substituted 6-trifluoromethylpurines and 1-deazapurines. [Thesis, fully internal, Universiteit van Amsterdam].
  • Läppchen, T., Pinas, V. A., Hartog, A. F., Koomen, G. J., Schaffner-Barbero, C., Andreu, J. M., Trambaiolo, D., Löwe, J., Juhem, A., Popov, A. V., & den Blaauwen, T. (2008). Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites. Chemistry & Biology, 15(2), 189-199. https://doi.org/10.1016/j.chembiol.2007.12.013
  • Rodenko, B., van der Burg, A. M., Wanner, M. J., Kaiser, M., Brun, R., Gould, M., de Koning, H. P., & Koomen, G. J. (2007). 2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities. Antimicrobial Agents and Chemotherapy, 51(11), 3796-3802. https://doi.org/10.1128/AAC.00425-07
  • Glavinas, H., Kis, E., Pal, A., Kovacs, R., Jani, M., Vagi, E., Molnar, E., Bansaghi, S., Kele, Z., Janaky, T., Bathori, G., von Richter, O., Koomen, G. J., & Krajcsi, P. (2007). ABCG2 (breast cancer resistance protein/mitoxantrone resistance-associated protein) ATPase assay: a useful tool to detect drug-transporter interactions. Drug Metabolism and Disposition, 35(9), 1533-1542. https://doi.org/10.1124/dmd.106.014605
  • Open Access
    Läppchen, T. (2007). Synthesis of GTP analogues and evaluation of their effect on the antibiotic target FtsZ and its eukaryotic homologue tubulin. [Thesis, fully internal, Universiteit van Amsterdam].
  • Rodenko, B., Detz, R. J., Pinas, V., Lambertucci, C., Brun, R., Wanner, M. J., & Koomen, G. J. (2006). Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues. Bioorganic & Medicinal Chemistry, 14(5), 1618-1629. https://doi.org/10.1016/j.bmc.2005.10.011
  • Rodenko, B., Koch, M., van der Burg, A. M., Wanner, M. J., & Koomen, G. J. (2005). The Mechanism of Selective Purine C-Nitration Revealed: NMR Studies Demonstrate Formation and Radical Rearrangement of an N7-Nitramine Intermediate. Journal of the American Chemical Society, 127(6), 5957-5963. https://doi.org/10.1021/ja042590x
  • Oezvegy-Laczka, C., Varady, G., Koebloes, G., Ujhelly, O., Cervenak, J., Schütz, J. D., Sorrentino, B. P., Koomen, G. J., Varadi, A., Nemet, K., & Sarkadi, B. (2005). Function-dependent Conformational Changes of the ABCG2 Multidrug Transporter Modify Its Interaction with a Monoclonal Antibody on the Cell Surface. The Journal of Biological Chemistry, 280(6), 4219-4227. https://doi.org/10.1074/jbc.M411338200
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