(Mal-) adaptive synchronization in the human brain Signatures of neural oscillations in psychiatric and normative populations

Open Access
Authors
  • K. Bangel
Supervisors
  • D.A.J.P. Denys
  • M. Olff
Cosupervisors
  • D.J.A. Smit
  • A. Mazaheri
Award date 10-03-2025
Number of pages 127
Organisations
  • Faculty of Medicine (AMC-UvA)
Abstract
Neural oscillations are a fundamental mechanism to orchestrate precise temporal coordination in the brain and slightly different patterns in neural oscillations may have far-reaching consequences for cognitive functioning. The goal of this thesis is to elucidate the neuronal oscillatory mechanisms that reflect cognitive processing. I investigated the cognitive mechanism of attention in normative groups as well as in people with psychiatric disorders namely, post-traumatic stress disorder and autism spectrum disorder. I aim to shed light on attentional resource allocation in various cognitive paradigms as well as neural mechanisms at rest. For the final chapter, I had the unique opportunity to investigate neural power and connectivity in patients with obsessive-compulsive disorder while they received deep brain stimulation treatment.
Document type PhD thesis
Language English
Downloads
Thesis (complete) (Embargo up to 2027-03-10)
Chapter 2: Expect to neglect: Cross-modal attention allocation in anticipation of visual load (Embargo up to 2027-03-10)
Chapter 3: It’s all about the timing: Pre-target alpha suppression effect of cue load is modulated by cue-target interval length (Embargo up to 2027-03-10)
Chapter 7: Acute effects of deep-brain stimulation on brain function in obsessive-compulsive disorder (Embargo up to 2027-03-10)
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