Additional file 1 of Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline

Additional file 1: Table S1. List of metabolites analyzed in serum samples. Table S2. Details about the ApoE stratification of the study population. Table S3. Average neuropsychological test scores at each visit along the follow-up (i.e., V = 0, 2, 4, 7, 10 and 12 years) in cases and matched controls individuals. Values are expressed as mean (SD). Table S4. Concentrations within each study group of the fatty acid-related metabolites that were identified by lineal modeling to be associated with cognitive decline, ApoE-ε4 genotype and sex. The results are expressed as mean (SD) in μg L-1. Table S5. Concentrations within ApoE-stratified subgroups of the fatty acid-related metabolites that were identified by lineal modeling to be associated with cognitive decline, ApoE-ε4 genotype and sex. The results are expressed as mean (SD) in μg L-1. Figure S1. Pearson’s correlation analysis between metabolomics, biochemical and neuropsychological variables within the four study groups stratified according to the ApoE-ε4 genotype and sex: female non-carriers (A), male non-carriers (B), female carriers (C), and male carriers (D).