Childhood initiated statin therapy in familial hypercholesterolemia

Thesis

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Stellingen

Title pages

Table of contents

Chapter 1: General introduction

Chapter 2: Statins and other lipid-lowering drugs in children at increased risk for cardiovascular disease

Chapter 3: Molecular basis of autosomal dominant hypercholesterolemia: Assessment in a large cohort of hypercholesterolemic children

Chapter 4: Follow-up of children diagnosed with familial hypercholesterolemia in a national genetic screening program

Chapter 5: A systematic review and meta-analysis of statin therapy in children with familial hypercholesterolemia

Chapter 6: Efficacy and safety of rosuvastatin therapy for children with familial hypercholesterolemia

Chapter 7: Rosuvastatin lowers coenzyme Q10 levels, but not mitochondrial adenosine triphosphate synthesis, in children with familial hypercholesterolemia

Chapter 8: Efficacy and safety of coadministration of ezetimibe and simvastatin in adolescents with heterozygous familial hypercholesterolemia

Chapter 9: Early initiation of statin therapy and the natural history of familial hypercholesterolemia: A ten year follow-up study

Chapter 10: Ten years of statin therapy initiated in childhood: Tolerability and adherence of patients with familial hypercholesterolemia

Chapter 11: Statins: Also indicated during childhood!

Chapter 12: Pregnancy in women suffering from familial hypercholesterolemia: A harmful period for both mother and newborn?

Chapter 13: Inheritance pattern of familial hypercholesterolemia and markers of cardiovascular risk

Chapter 14: Summary

Chapter 15: General discussion

Nederlandse samenvatting (ook voor niet ingewijden)

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Dankwoord

Curriculum vitae

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