Macrophage migration inhibitory factor, infection, the brain, and corticosteroids
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| Publication date | 2009 |
| Journal | Critical Care |
| Volume | Issue number | 13 | 4 |
| Pages (from-to) | 170 |
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| Abstract | Bacterial meningitis is a complex disorder in which injury is caused, in part, by the causative organism and, in part, by the host's own inflammatory response. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine and a neuro-endocrine mediator that might play a role in pneumococcal meningitis. Here, we discuss the role of MIF in infection, the brain, and corticosteroids and conclude that experimental meningitis studies have to determine whether MIF is a potential target for adjunctive therapy in pneumococcal meningitis |
| Document type | Article |
| Published at | https://doi.org/10.1186/cc7970 |
| Downloads |
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