Pathophysiology and management of coagulation disorders in critical care medicine

Thesis

Cover

Titlepage

Contents

Chapter 1 General Introduction and Outline of this Thesis

Chapter 2 Current Drug Treatment Strategies for Disseminated Intravascular Coagulation

Chapter 3 Coagulation abnormalities in sepsis: relation with inflammatory responses

Chapter 4 Tissue factor pathway inhibitor (TFPI) dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia

Chapter 5 Tissue factor pathway inhibitor (TFPI) does not influence inflammatory pathways during human endotoxemia

Chapter 6 Activation of coagulation by administration of recombinant factor VIIa elicits interleukin (IL)-6 and IL-8 release in healthy human subjects

Chapter 7 The In Vivo Kinetics of Tissue Factor mRNA Expression during Human Endotoxemia: Relationship with Activation of Coagulation

Chapter 8 Effects of Different Plasma Substitutes on Blood Coagulation. A comparative review

Chapter 9 Impaired Haemostasis by Intravenous Administration of a Gelatin-based Plasma Expander in Human Subjects

Chapter 10 Decreased Circulating Levels of Von Willebrand Factor after Intravenous Administration of a Rapidly Degradable Hydroxyethyl Starch (HES 200/0.5/6) in Healthy Human Subjects

Chapter 11 Pharmacological Strategies to Decrease Excessive Blood Loss in Cardiac Surgery: A Meta-Analysis of Clinically Relevant End Points

Summary

Samenvatting

Dankwoord

Stellingen behorende bij het proefschrift

Cover