Megakarocyte formation in vitro to expand and explore

Authors	S. van den Oudenrijn
Supervisors	A.E.G.Kr. von dem Borne
Cosupervisors	M. de Haas
Award date	13-03-2001
ISBN	9090145761 9789090145761
Number of pages	178
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Geneeskunde, Immunologie
Downloads	Thesis Cover Titlepage Contents Chapter 1 Scope of this thesis Chapter 2 Thrombopoietin and ex vivo expansion of megakaryocytes Chapter 3 A combination of Megakaryocyte Growth and Development Factor and interleukin-1 is sufficient to culture large numbers of megakaryocytic progenitors and megakaryocytes for transfusion purposes Chapter 4 Differences in megakaryocyte expansion potential between CD34+ stem cells derived from cord blood, peripheral blood and bone marrow from adult and children Chapter 5 Influence of medium components on ex vivo megakaryocyte expansion Chapter 6 Mutations in the thrombopoietin receptor, Mpl, in children with congenital amegakaryocytic thrombocytopenia Chapter 7 Three parameters: plasma thrombopoietin levels, plasma glycocalicin levels and megakaryocyte culture, distinguish between different causes of congenital thrombocytopenia Chapter 8 Aberrant processing and folding of Mpl due to mutations associated with congenital amegakaryocytic thrombocytopenia Chapter 9 Summary and general discussion Chapter 10 Samenvatting Dankwoord Cover
Permalink to this page

Back

UvA-DARE