Genesis of life-threatening ventricular arrythmias during the delayed phase of acute myocardial ischemia. Role of cellular electrical coupling and myocardial heterogeneities

Authors	J.R. de Groot
Supervisors	M.J. Janse
Cosupervisors	R. Coronel
Award date	28-06-2001
ISBN	9090145974 9789090145976
Number of pages	155
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Geneeskunde, CRIA
Language	English
Downloads	Thesis Cover Stellingen Titlepage CONTENTS 1 GENERAL INTRODUCTION 2 EXPERIMENTAL MODELS, ANIMALS, MATERIALS, AND METHODS 3 LATE VENTRICULAR ARRHYTHMIAS DURING ACUTE REGIONAL ISCHEMIA IN THE ISOLATED BLOOD PERFUSED PIG HEART. ROLE OF ELECTRICAL CELLULAR COUPLING. 4 ROLE OF SUBEPICARDIAL HETEROGENEITIES IN THE GENESIS OF LATE VENTRICULAR ARRHYTHMIAS DURING ACUTE MYOCARDIAL ISCHEMIA. 5 DELAYED VENTRICULAR ARRHYTHMIAS DURING ACUTE MYOCARDIAL ISCHEMIA RELATE TO MACROREENTRANT ACTIVATION. 6 METABOLIC AND ELECTROPHYSIOLOGICAL DIFFERENCES BETWEEN ISOLATED SINGLE CELLS AND CELL PAIRS IN RESPONSE TO METABOLIC INHIBITION IN NORMAL AND HYPERTROPHIC RABBIT LEFT VENTRICULAR MYOCYTES 7 INITIATION OF DELAYED, ISCHEMIA-INDUCED LIFE THREATENING ARRHYTHMIAS: FOCAL ACTIVITY RELATED TO LEFT VENTRICULAR MECHANICAL FUNCTION 8 SYNTHESIS 9 SUMMARY/NEDERLANDSE SAMENVATTING DANKWOORD Cover
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