Evaluation of fluorescence measurement techniques for tumour detection in vivo

Authors	A.E. Saarnak
Supervisors	M.J.C. van Gemert
Cosupervisors	H.J.C.M. Sterenborg
Award date	12-01-1999
Number of pages	127
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Language	English
Downloads	Thesis Cover Titlepage Contents Chapter 1. Introduction Chapter 2. Evaluation of spectral correction techniques for fluorescence measurements on pigmented lesions in vivo Chapter 3. Individual variations in fluorescence of piglet skin in vivo after oral administration of ALA Chapter 4. Fluorescence measurements of mTHPC in basal cell carcinoma and two malignant melanomas using the Double Ratio and the Normalised Fluorescence Ratio techniques Chapter 5. Photodynamic therapy with mTHPC for basal cell carcinoma: A dose finding study Chapter 6. Influence of tumour depth, blood absorption and autofluorescence on measurements of exogenous fluorophores in tissue Chapter 7. Effective treatment of liver metastases with photodynamic therapy, using the second generation photosensitizer meta-tetra(hydroxyphenyl)chlorin (mTHPC), in a rat model Chapter 8. Correlation between fluorescence in vivo and photosensitiser concentration in rat liver and tumour Chapter 9. Mathematical evaluation of fluorescence ratio techniques using an analytical model Chapter 10. Discussion and conclusions Abstract Samenvatting Nawoord Curriculum Vitae
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