Signaling in leokocyte transendothelial migration: a roadmap for homing of progenitor cells

Authors	J.D. van Buul
Supervisors	D. Roos
Cosupervisors	P.L. Hordijk C.E. van der Schoot
Award date	14-05-2004
Number of pages	150
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Immunologie
Language	English
Downloads	Thesis (complete) Front cover ERRATA Stellingen behorende bij het proefschrift Title pages Contents Preface SCOPE OF THE THESIS Chapter 1 SIGNALLING IN LEUKOCYTE TRANSENDOTHELIAL MIGRATION. Chapter 2 LEUKOCYTE-ENDOTHELIUM INTERACTION PROMOTES SDF-1-DEPENDENT POLARIZATION OF CXCR4. Chapter 3 CXCR4 IS SUFFICIENT FOR BONE MARROW SPECIFIC HOMING AND ENGRAFTMENT BY HEMATOPOIETIC PROGENITOR CELLS. Chapter 4 VCAM-1-MEDIATED RAC SIGNALING CONTROLS ENDOTHELIAL CELL-CELL CONTACTS AND LEUKOCYTE TRANSMIGRATION. Chapter 5 MIGRATION OF HUMAN HEMATOPOIETIC PROGENITOR CELLS ACROSS BONE-MARROW ENDOTHELIUM IS REGULATED BY VE-CADHERIN. Chapter 6 REACTIVE OXYGEN SPECIES MEDIATE RAC-INDUCED LOSS OF CELL-CELL ADHESION IN PRIMARY HUMAN ENDOTHELIAL CELLS. Chapter 7 VE-CADHERIN AND RAC1 ACT IN CONCERT TO CONTROL ENDOTHELIAL CELL-CELL ADHESION. Chapter 8 ICAM-3 ACTIVATION MODULATES CELL-CELL CONTACTS OF HUMAN BONE-MARROW ENDOTHELIAL CELLS. Chapter 9 REGULATION OF THE OXIDASE SYSTEM IN HUMAN ENDOTHELIAL CELLS. Chapter 10 DISCUSSION AND CONCLUSION. Summary SAMENVATTING VOOR NIET-INGEWIJDEN Dankwoord Loftrompet Back cover
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