Improving the application of aerobic exercise in neuromuscular diseases From laboratory exercise testing to training in the home environment

Aerobic exercise is important in rehabilitation of people with neuromuscular diseases to improve physical fitness, which is often reduced in this population. However, several challenges limit the broader and more effective implementation of aerobic exercise within rehabilitation practice. These challenges raise important questions: Which exercise tests are best suited to tailor and evaluate aerobic exercise programs for each individual? How can such tests be made more widely accessible, particularly in settings with limited access to specialized equipment? And how can people be better supported and monitored when training at home?
In this thesis, we investigated these questions with the aim of improving the clinical application of aerobic exercise in people with neuromuscular diseases. We conducted a series of studies focusing on key components of aerobic exercise, including exercise testing both inside and outside a laboratory setting, as well as training in the home environment. The findings of this thesis provide guidance on how to apply exercise testing to prescribe and evaluate aerobic exercise programs, even in rehabilitation settings with limited resources. Moreover, we demonstrated that home-based aerobic exercise can be effectively supported and monitored through e-health solutions.