Inhibition of cytokine production by methotrexate. Studies in healthy volunteers and patients with rheumatoid arthritis

Authors	S. de Lathouder
Supervisors	L.A. Aarden
Cosupervisors	B.A.C. Dijkmans
Award date	03-06-2004
Number of pages	119
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Immunologie
Language	English
Downloads	Thesis Cover Titlepage Contents abbreviations Chapter 1 General introduction Chapter 2. Inhibition of cytokine production by methotrexate Chapter 3. Mycophenolic acid and methotrexate inhibit lymphocyte cytokine production via different mechanisms. Chapter 4. MTX induced inhibition of cytokine production is not mediated by adenosine. Chapter 5 A differential effect of MPA on monokine production, evidence for induction os IL-1β production Chapter 6 Bioassay for detection of methotrexate in serum. Chapter 7 In vitro T-cell activation is decreased two hours after MTX intake and does not predict clinical response. Chapter 8 General discussion Chapter 9 Summary Chapter 10 Samenvatting Dankwoord Curriculum vitae Cover
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