Molecular genetic alterations in gastrointestinal polyposis syndromes: with emphasis on the Peutz-Jeghers syndrome

Authors	M.M. Entius
Supervisors	G.J.A. Offerhaus J.H.P. Wilson
Award date	21-09-2000
Number of pages	101
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: CLDO
Language	English
Downloads	Thesis Cover Titlepage Table of Contents Abbreviations: Chapter 1 General Introduction and Outline of the Thesis Chapter 2 Upper Gastrointestinal Polyps in Familial Adenomatous Polyposis Chapter 3 Molecular and Phenotypic Markers of Hamartomatous Polyposis Syndromes in the Gastrointestinal Tract Chapter 4 Multiple Hyperplastic Polyps in the Stomach: Evidence for Clonality and Neoplastic Potential Chapter 5 Peutz-Jeghers Polyps, Dysplasia and K-ras codon 12 mutations Chapter 6 Peutz-Jeghers Syndrome: 78-year Follow-Up of the Original Family Chapter 7 Germline and Somatic Mutations of the STK11/LKB1 Peutz-Jeghers Gene in Pancreatic and Biliary Cancers Chapter 8 Pathogenesis of Adenocarcinoma in Peutz-Jeghers Syndrome Chapter 9 Novel Mutations in the LKB1/STK11 Gene in Dutch Peutz-Jeghers Families Chapter 10 Molecular Genetic Alterations in Hamartomatous Polyps and Carcinomas of Peutz-Jeghers Patients Chapter 11 Microsatellite Instability and Expression of hMLH-1 and hMSH-2 in Sebaceous Gland Carcinomas as Markers for Muir-Torre Syndrome Summary / Samenvatting NAWOORD Cover
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