Transcriptional regulation of the human interleukin-12 receptor beta2 gene

Authors	J.G.I. van Rietschoten
Supervisors	M.L. Kapsenberg
Cosupervisors	M.T. den Hartog E.A. Wierenga
Award date	24-05-2002
ISBN	9090158588 9789090158587
Number of pages	167
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Immunologie
Language	English
Downloads	Thesis Cover STELLINGEN Titlepage CONTENTS Chapter 1 GENERAL INTRODUCTION Chapter 2 GENOMIC ORGANIZATION OF THE HUMAN INTERLEUKIN-12 RECEPTOR ß2-CHAIN GENE Chapter 3 SILENCER ACTIVITY OF NFATc2 IN THE INTERLEUKIN-12 RECEPTOR ß2 PROXIMAL PROMOTER IN HUMAN T HELPER CELLS Chapter 4 INTERLEUKIN-12-INDUCED REVERSAL OF HUMAN TH2 CELLS IS ACCOMPANIED BY FULL RESTORATION OF IL-12 RESPONSIVENESS AND LOSS OF GATA-3 EXPRESSION Chapter 5 GATA3 DOES NOT SUPPRESS HUMAN IL-12Rß2 PROMOTER ACTIVITY Chapter 6 A NOVEL POLYMORPHIC GATA SITE IN THE HUMAN IL-12Rß2 PROMOTER REGION AFFECTS TRANSCRIPTIONAL ACTIVITY Chapter 7 GENERAL DISCUSSION SUMMARY SAMENVATTING DANKWOORD CURRICULUM VITAE List of Publications Notes Cover
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