Gastrointestinal polyposis syndromes

Gastrointestinal polyposis syndromes

Authors	J.J. Keller
Supervisors	G.J.A. Offerhaus F.M. Giardello
Award date	20-06-2003
Number of pages	141
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: CLDO
Language	English
Downloads	Thesis Cover Titlepage Table of Contents Chapter 1 General Introduction Molecular and phenotypic aspects of gastrointestinal polyposis syndromes Chapter 2 Chemoprevention strategies using NSAIDs and COX-2 inhibitors Chapter 3 Rectal epithelial apoptosis in familial adenomatous polyposis patients treated with sulindac. Chapter 4 Rectal epithelial apoptosis does not predict response to sulindac treatment or polyp development in presymptomatic FAP patients Chapter 5 Molecular Analysis of Sulindac-Resistant Adenomas in Familial Adenomatous Polyposis Chapter 6 NSAIDs target nuclear β-catenin accumulation and Wnt signaling in adenomas of patients with familial adenomatous polyposis and in colorectal cancer cell lines Chapter 7 Jan Peutz, Harold Jeghers and a remarkable combination of polyposis and pigmentation of the skin and mucous membranes Chapter 8 Molecular Genetic Alterations in Hamartomatous Polyps and Carcinomas of Patients with Peutz-Jeghers Syndrome Chapter 9 COX-2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas Chapter 10 Molecular genetic evidence for an association between nasal polyposis and Peutz-Jeghers syndrome Chapter 11 Nasal polyposis in PJS: a distinct entity with pre-malignant potential? Chapter 12 The diagnostic value of mucocutaneous pigmentation in Peutz-Jeghers syndrome Chapter 13 Cancer risk in Peutz-Jeghers syndrome Summary and concluding remarks Samenvatting Curriculum vitae Publicaties Nawoord Gastrointestinal Polyposis Syndromes Stellingen hehorende bij het proefschrift Cover
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Gastrointestinal polyposis syndromes