Coherent anti-Stokes Raman scattering microscopy for quantitative characterization of mixing and flow in microfluidics

Open Access
Authors
  • D. Schafer
  • M. Müller
  • M. Bonn
  • D.W.M. Marr
Publication date 2009
Journal Optics Letters
Volume | Issue number 34 | 2
Pages (from-to) 211-213
Organisations
  • Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Abstract We present an optical, noninvasive and label-free approach to characterize flow profiles in microfluidic devices. Coherent anti-Stokes Raman scattering signals were used to map the mass transport in a microfluidic device that was then related back to the local flow rate of dilute solutes having constant fluid properties. Flow characterization was demonstrated in two common types of microfluidic devices, polydimethylsiloxane/glass square channels and wet-etched glass tapered channels.
Document type Article
Published at https://doi.org/10.1364/OL.34.000211
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