Hormones in neurodegeneration, neuroprotection, and neurogenesis
ISBN
9783527326273
Pages (from-to)
103-120
Number of pages
375
Publisher
Weinheim: Wiley-VCH
Organisations
Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Abstract
In this chapter, we will review changes in structural plasticity of the adult hippocampus during stress and exposure to glucocorticoids (GCs). We further discuss the protective and normalizing role of glucocorticoid receptor (GR) antagonist treatment under these conditions and its implications for disorders such as depression and diabetes mellitus.