The use of surrogate markers in the antiretroviral treatment of HIV-1 infection

Authors	A.M. Hill
Supervisors	J.M.A. Lange
Award date	27-06-2003
Number of pages	123
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Infectieziekten
Language	English
Downloads	Thesis Cover Titlepage Table of Contents CHAPTER 1 Introduction CHAPTER 2 Reductions in HIV-1 disease progression for zidovudine/lamivudine relative to control treatments: a meta-analysis of controlled trials CHAPTER 3 CD4 cell counts in seven laboratory workers CHAPTER 4 Prediction of HIV-1 RNA suppression and its durability during treatment with zidovudine/lamivudine. CHAPTER 5 Prediction of progression to AIDS with serum HIV-1 RNA and CD4 count. CHAPTER 6 HIV-1 RNA, CD4 cell count and the risk of progression to AIDS and death during treatment with HIV-1 reverse transcriptase inhibitors. CHAPTER 7 The effects of lamivudine treatment on HIV-1 disease progression are highly correlated with plasma HIV-1 RNA and CD4 cell count CHAPTER 8 Meta-analysis of antiretroviral effects on HIV-1 RNA, CD4 cell count and progression to AIDS or death. CHAPTER 9 Analysis of HIV-1 clinical trials: statistical magic? CHAPTER 10 Practical implication for the interpretation of minimaum plasma concentration/inhibitory concentration ratios CHAPTER 11 Discussion CHAPTER 12 Summary CHAPTER 13 Samenvatting (Summary in Dutch) Bibliography Acknowledgements Cover
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