Limitations of current antiretroviral therapy in HIV-1 infection: the search for new strategies

Thesis

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Titlepage

Contents

CHAPTER 1 Introduction

CHAPTER 2 Dynamics of the pool of infected resting CD4 HLA-DR T lymphocytes in patients who started a triple class five-drug antiretroviral regimen during primary HIV-1 Infection

CHAPTER 3 Limited penetration of lopinavir into seminal plasma of HIV-1-infected men

CHAPTER 4 TMC125 exerts similar initial antiviral potency as a five-drug, triple class antiretroviral regimen

CHAPTER 5 Highly active antiretroviral therapy with or without mycophenolate mofetil in treatment naïve HIV-1 patients

CHAPTER 6 No detrimental immunological effects of mycophenolate mofetil and HAART in treatment naïve acute and chronic HIV-1 infected patients

CHAPTER 7 Effect of mycophenolate mofetil on the pharmacokinetics of antiretroviral drugs and the intracellular nucleoside triphosphate pools

CHAPTER 8 HIV-1 seroreversion in an HIV-1 seropositive patient treated during acute infection with HAART and mycophenolate mofetil

CHAPTER 9 P-glycoprotein in human immunodeficiency virus type 1 infection and therapy

CHAPTER 10 Antiviral activity of HIV-1 protease inhibitors nelfinavir and indinavir in vivo is not influenced by P-glycoprotein activity on CD4+ T-cells

CHAPTER 11 Summary & Discussion

Co-authors

Dankwoord

Curriculum Vitae

List of publications

Stellingen behorende bij het proefschrift

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