Complete Genome Sequence of the Itraconazole Decreased Susceptible Madurella fahalii Type-Strain CBS 129176

Open Access
Authors
  • M. Konings
  • B. Gerrits van den Ende
  • M.W.J. Raats
  • A.H. Fahal
  • W.W.J. van de Sande
  • F. Hagen
Publication date 02-2024
Journal Mycopathologia
Article number 6
Volume | Issue number 189 | 1
Number of pages 4
Organisations
  • Faculty of Science (FNWI) - Institute for Biodiversity and Ecosystem Dynamics (IBED)
Abstract

Madurella fahalii is a causative agent of the implantation mycosis mycetoma with decreased susceptibility to itraconazole, the preferred therapeutic drug to combat mycetoma. Here, we report the M. fahalii type-strain CBS 129176 genome assembly and annotation to identify a glutamic acid insert near the azole-binding pocket in the Cyp51A protein.

Document type Article
Language English
Published at https://doi.org/10.1007/s11046-023-00807-0
Other links https://www.scopus.com/pages/publications/85182443171
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s11046-023-00807-0 (Final published version)
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