Intestinal cholesterol transport: Measuring cholesterol absorption and its reverse

Open Access
Authors
  • L. Jakulj
Supervisors
Cosupervisors
  • M.N. Vissers
Award date 24-05-2013
ISBN
  • 9789082043709
Number of pages 176
Publisher 's-Hertogenbosch: Boxpress
Organisations
  • Faculty of Medicine (AMC-UvA)
Abstract Intestinal cholesterol transport might serve as an attractive future target for cardiovascular disease reduction, provided that underlying molecular mechanisms are more extensively elucidated, combined with improved techniques to measure changes in cholesterol fluxes and their possible anti-atherosclerotic consequences.
In the series of experiments described in this thesis we attempt to establish valid techniques to measure intestinal cholesterol fluxes and to generate hypotheses on the mechanisms that underlie interventions targeting this particular part of human cholesterol homeostasis.
Document type PhD thesis
Note Research conducted at: Universiteit van Amsterdam
Language English
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