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Autophagy-modulating aminosteroids isolated from the sponge Cliona celata
Autophagy-modulating aminosteroids isolated from the sponge Cliona celata
Authors
R.A. Keyzers
J. Daoust
M.T. Davies-Coleman
R. van Soest
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A. Balgi
E. Donohue
M. Roberge
R.J. Andersen
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Publication date
2008
Journal
Organic Letters
Volume | Issue number
10 | 14
Pages (from-to)
2959-2962
Organisations
Faculty of Science (FNWI)
Abstract
Clionamines A−D (1−4), new aminosteroids that modulate autophagy, have been isolated from South African specimens of the sponge Cliona celata. Clionamine D (4) has an unprecedented spiro bislactone side chain.
Document type
Article
Published at
https://doi.org/10.1021/ol800937u
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