Subcellular localization of the hum isoprenoid biosynthesis pathway

Authors	S. Hogenboom
Supervisors	R.J.A. Wanders
Cosupervisors	H.R. Waterham
Award date	13-01-2004
Number of pages	128
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: GEMO
Downloads	Thesis Cover Titlepage CONTENTS ABBREVIATIONS 1 GENERAL INTRODUCTION: THE SUBCELLULAR LOCALIZATION OF THE ISOPRENOID BIOSYNTHESIS PATHWAY IN MAMMALS, AN OVERVIEW 2 ABSENCE OF FUNCTIONAL PEROXISOMES DOES NOT LEAD TO DEFICIENCY OF ENZYMES INVOLVED IN CHOLESTEROL BIOSYNTHESIS 3 CHOLESTEROL BIOSYNTHESIS IS NOT DEFECTIVE IN PEROXISOME BIOGENESIS DEFECTIVE FIBROBLASTS 4 MEVALONATE KINASE IS A CYTOSOLIC ENZYME IN HUMANS 5 PHOSPHOMEVALONATE KINASE IS A CYTOSOLIC PROTEIN IN HUMANS 6 HUMAN MEVALONATE PYROPHOSPHATE DECARBOXYLASE IS EXCLUSIVELY LOCALIZED IN THE CYTOSOL SUMMARY & SAMENVATTING VOOR IEDEREEN DANKWOORD CURRICULUM VITAE Cover
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