Thyroid problems in pediatric oncology : damage, prevention and consequences

Thyroid problems in pediatric oncology : damage, prevention and consequences

Authors	H.M. van Santen
Supervisors	J.J.M. de Vijlder
Cosupervisors	T. Vulsma J. de Kraker
Award date	26-01-2005
ISBN	9090189432 9789090189437
Number of pages	429
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: GEMO
Downloads	Thesis Cover Stellingen behorende bij het proefschrift Titlepage Contents Chapter 1 General Introduction Part 1 Thyroid damage after treatment with 131I-MIBG Chapter 2 High incidence of thyroid dysfunction despite prophylaxis with potassium iodide during 131I-meta-iodobenzylguanidine treatment in children with neuroblastoma Chapter 3 Endocrine late effects after multi-modality treatment, including 131I-MIBG, for neuroblastoma Chapter 4 Improved radiation protection of the thyroid gland with thyroxine, methimazole and potassium iodide during diagnostic and therapeutic use of radiolabeled metaiodobenzylguanidine in children with neuroblastoma Part 2 Thyroid damage after external radiation therapy Chapter 5 The effect of cervical X-irradiation on activity index of thyrocytes and plasma TSH; a pre-clinical model for radiation-induced thyroid damage Chapter 6 Endocrine intervention during irradiation does not prevent damage to the thyroid gland Part 3 Consequences of thyroid carcinoma during childhood Chapter 7 Frequent adverse events after treatment for childhood-onset differentiated thyroid carcinoma: a single institute experience Chapter 8 Case History Disseminated medullary thyroid caricinoma despite early thyroid surgery in the MEN-2A syndrome Part 4 Thyroid hormones during and after chemotherapy Chapter 9 The changing thyroid hormone state in children receiving chemotherapy Chapter 10 No damaging effect of chemotherapy in addition to radiotherapy on the thyroid axis in young adult survivors of childhood cancer Part 5 Prevention of damage to the thyroid gland: review of the literature, general discussion and future perspectives Chapter 11a Effectiveness of preventive strategies for thyroid damage due to radiation therapy, Part I: Review of human studies Chapter 11b Effectiveness of preventive strategies for thyroid damage due to radiation therapy Part II: Review of animal studies Chapter 12 General Discussion & Future Perspectives Appendices English summary Nederlandse samenvatting Dankwoord Acknowledgments Curriculum Vitae Cover
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Thyroid problems in pediatric oncology : damage, prevention and consequences