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  2. Epigenetic mechanisms regulating the inflammatory response

Epigenetic mechanisms regulating the inflammatory response

Open Access
Authors
  • R. Schilderink
Supervisors
  • W.J. de Jonge
Cosupervisors
  • M.P.J. de Winther
Award date 25-05-2018
ISBN
  • 9789402810196
Number of pages 201
Organisations
  • Faculty of Medicine (AMC-UvA)
Document type PhD thesis
Language English
Downloads
Thesis (complete)
Front matter
Chapter 1: General introduction
Chapter 2: Dietary inhibitors of histone deacetylases in intestinal immunity and homeastasis
Chapter 3: The SCFA butyrate stimulates the epithelial production of retinoic acid via inhibition of epithelial HDAC
Chapter 4: BET bromodomain inhibition reduces maturation and enhances tolerogenic properties of human and mouse dendritic cells
Chapter 5: HDAC3 mediates cytokine secretion and mRNA stability in mouse dendritic cells
Chapter 6: HDAC3 activity is critical for inflammatory responses in human monocytes and macrophages
Chapter 7: miR-511-3p, embedded in the macrophage mannose receptor gene, contributes to intestinal inflammation
Chapter 8: General discussion
Summary; Samenvatting; Publications; PhD portfolio; About the author; Dankwoord
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