Beyond extinction: erasing human fear responses and preventing the return of fear
| Authors |
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| Publication date |
2009
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| Journal |
Nature Neuroscience
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| Volume | Issue number |
12 | 3
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| Pages (from-to) |
256-258
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| Organisations |
-
Faculty of Social and Behavioural Sciences (FMG) - Psychology Research Institute (PsyRes)
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| Abstract |
Animal studies have shown that fear memories can change when recalled, a process referred to as reconsolidation. We found that oral administration of the beta-adrenergic receptor antagonist propranolol before memory reactivation in humans erased the behavioral expression of the fear memory 24 h later and prevented the return of fear. Disrupting the reconsolidation of fear memory opens up new avenues for providing a long-term cure for patients with emotional disorders.
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| Document type |
Article
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| Published at |
https://doi.org/10.1038/nn.2271
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