Experimental and clinical studies on collateral and epicardial flow in obstructive arterial disease

Thesis

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Titlepage

Table of contents

Chapter 1 Introduction and outline

Part I EXPHRIMENTAL STUDIES ON MODULATION OF ARTERIOGENESIS

Chapter 2 Abnormal monocyte recruitment and collateral artery formation in monocyte chemoattractant protein 1 deficient mice

Chapter 3 Normal arterial responsiveness and remodeling after modulation of TR3 orphan receptor expression

Chapter 4 CD44 controls arteriogenesis by promoting leukocyte extravasation and stabilizing FGF-2 and PDGF-B

Chapter 5 Invasive and non invasive evaluation of spontaneous arteriogenesis in a novel porcine model for peripheral arterial obstructive disease

Chapter 6 Modulation of collateral artery growth in a porcine hind limb ligation model using MCP-1

Part II CLINICAL STUDIES ON INTRACORONARY HEMODYNAMICS IN ELECTIVE ANGIOPLASTY

Chapter 7 Clinical and hemodynamic determinants of flow velocity reserve in angiographically normal coronary arteries

Chapter 8 The immediate and long-term effect of optimal balloon angioplasty on the absolute coronary blood flow velocity reserve: a subanalysis of the DEBATE-study

Chapter 9 Coronary hemodynamics of stent implantation following suboptimal and optimal balloon angioplasty

Chapter 10 Optimized stent implantation according to intracoronary Doppler derived parameters

Chapter 11 Coronary flow velocity reserve after percutaneous interventations is predictive of peri procedural outcome

Chapter 12 Summary and interpretation of the results

Chapter 13 Samenvatting en interpretatie van de resultaten

Dankwoord

Curriculum Vitae

List of publications

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