Regulation of metabolism by amino acid dependant signal transduction

Thesis

Cover

Abbreviations

Titlepage

Contents

Chapter 1 Introduction

Chapter 2 The tumor suppressor PTEN positively regulates macroautophagy by inhibiting the phosphatidylinositol 3-kinase / protein kinase B pathway

Chapter 3 Inhibition of autophagic proteolysis by inhibitors of phosphatidylinositol 3-kinase can interfere with the regulation of glycogen synthesis in isolated hepatocytes

Chapter 4 Hepatic amino acid-dependent signalling is under the control of AMP-dependent protein kinase

Chapter 5 Interactions between amino acids and insulin on the PI 3-kinase/PKB/mTOR/p70S6 kinase pathway in rat hepatocytes

Chapter 6 Studies on leucine-dependent activation of the mTOR/p70S6 kinase pathway

Chapter 7 General Discussion: Amino acids, signalling and the regulation of metabolism

Summary

Samenvatting voor de leek

Dankwoord

Cover