Genetics and therapy of familial hypercholesterolemia

Authors	P.R.W. de Sauvage Nolting
Supervisors	J.J.P. Kastelein H.R. Büller
Award date	11-12-2002
ISBN	9064640858 9789064640858
Number of pages	173
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: CRIA
Language	English
Downloads	Thesis Cover Titlepage CONTENTS CHAPTER 1 General introduction CHAPTER 2 Prevalence and significance of cardiovascular risk factors in a large cohort of patients with familial hypercholesterolemia CHAPTER 3 Serum bilirubin in familial hypercholesterolemia. A new risk marker for cardiovascular disease? CHAPTER 4 Two-year efficacy and safety of simvastatin 80 mg in familial hypercholesterolemia CHAPTER 5 Baseline lipid values partly determine the response to high-dose simvastatin in patients with familial hypercholesterolemia CHAPTER 6 Elevated remnant-like particles in heterozygous familial hypercholesterolemia and response to statin therapy CHAPTER 7 Regression of carotid and femoral intima-media thickness in familial hypercholesterolemia CHAPTER 8 Homocysteine and Atherosclerosis CHAPTER 9 Effects of simvastatin on coagulation and fibrinolysis in relation to intima-media thickness in patients with familial hypercholesterolemia CHAPTER 10 The effect of the LDL-receptor gene mutation on clinical phenotype and response to simvastatin 80 mg treatment CHAPTER 11 Summary Samenvatting Investigators list Dankwoord Curriculum vitae Bijlage Cover
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