Opacity proteins of Neisseria meningitides: structure-function relationship and vaccine potential

Thesis

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Titlepage

Contents

1 General introduction

2 Conformational analysis of opacity proteins from Neisseria meningitidis

3 Mapping the binding domains on meningococcal Opa proteins for CEACAM1 and CEA receptors

4 Functional activity of antibodies against recombinant Opaj protein from Neisseria meningitidis

5 Intranasal immunisation of mice with liposomes containing recombinant meningococcal OpaB and OpaJ proteins

6 CEACAM receptor specificity of neisserial Opa proteins expressed by E.coli determines the fate of bacteria during interaction with human neutrophils

7 General discussion and concluding remarks

Summary

Samenvatting

Dankwoord

Curriculum vitae

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