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  2. Intestinal barrier function: regulation of epithelial permeability and mucin expression

Intestinal barrier function: regulation of epithelial permeability and mucin expression

Open Access
Authors
  • L.E.M. Willemsen
Supervisors
  • S.J.H. van Deventer
Cosupervisors
  • E.A. van Tol
Award date 16-01-2004
ISBN
  • 9064642982
  • 9789064642982
Number of pages 126
Organisations
  • Faculty of Medicine (AMC-UvA)
Document type PhD thesis
Note Research conducted at: CLDO
Language English
Downloads
Thesis
Cover
Titlepage
Contents
List of abbreviations
1 General introduction
2 A coculture model mimicking the intestinal mucosa reveals a regulatory role for myofibroblasts in immune mediated barrier disruption
3 Short chain fatty acids stimulate epithelial mucin-2 expression through differential effects on prostaglandin E1 and E2 production by intestinal myofibroblasts
4 KGF selectively stimulates PGE1 secretion by intestinal myofibroblasts
5 IFN-y mediated barrier disruption involves claudin-2 degradation
6 Pivotal role for JNK MAPK in regulation of intestinal epithelial barrier integrity
7 Summarizing discussion
8 Samenvatting
Dankwoord
Curriculum Vitae
Stellingen behorende bij het proefschrift
Cover
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