Measuring treatment response in HIV-1 infection

Thesis

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Titlepage

Contents

CHAPTER 1 INTRODUCTION

CHAPTER 2 DISTINCT CHANGES IN HIV TYPE 1 RNA VERSUS P24 ANTIGEN LEVELS IN SERUM DURING SHORT-TERM ZIDOVUDINE THERAPY IN ASYMPTOMATIC INDIVIDUALS WITH AND WITHOUT PROGRESSION TO AIDS

CHAPTER 3 A COMPARISON OF SERUM HIV-1 RNA LEVELS AS MEASURED BY TWO QUANTITATIVE ASSAYS IN ZIDOVUDINE-TREATED, ASYMPTOMATIC, HIV-INFECTED INDIVIDUALS

CHAPTER 4 MULTICENTER COMPARISON OF THREE COMMERCIAL METHODS FOR QUANTIFICATION OF HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 RNA IN PLASMA

CHAPTER 5 DELTA: A RANDOMISED DOUBLE-BLIND CONTROLLED TRIAL COMPARING COMBINATIONS OF ZIDOVUDINE PLUS DIDANOSINE OR ZALCITABINE WITH ZIDOVUDINE ALONE IN HIV-INFECTED INDIVIDUALS

CHAPTER 6 HIV-1 VIRAL LOAD, PHENOTYPE, AND RESISTANCE IN A SUBSET OF DRUG-NAIVE PARTICIPANTS FROM THE DELTA TRIAL

CHAPTER 7 IMPROVEMENT OF CHRONIC DIARRHOEA IN PATIENTS WITH ADVANCED HIV-1 INFECTION DURING POTENT ANTIRETROVIRAL THERAPY

CHAPTER 8 DISCONTINUATION OF PNEUMOCYSTIS CARINII PNEUMONIA PROPHYLAXIS AFTER START OF HIGHLY ACTIVE ANTIRETROVIRAL THERAPY IN HIV-1 INFECTION

CHAPTER 9 ALTERNATIVE MULTIDRUG REGIMEN PROVIDES IMPROVED SUPPRESSION OF HIV-1 REPLICATION OVER TRIPLE THERAPY

CHAPTER 10 MINIMISATION TECHNOLOGIES IN RANDOMISED OPEN INTERVENTION STUDIES

CHAPTER 11 GENERAL DISCUSSION

SUMMARY

SAMENVATTING

Dankwoord

Curriculum Vitae

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