Molecular alterations in gastro-esophageal carcinogenesis

Thesis

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TABLE OF CONTENTS

CHAPTER 1 General Introduction

CHAPTER 2 Helicobacter pylori and Epstein-Barr virus infection and the p53 tumour suppressor pathway in gastric stump cancer compared with carcinoma in the non-operated stomach.

CHAPTER 3 K-ras Mutations in Gastric Stump Carcinomas and in Carcinomas from the Non-operated Stomach

CHAPTER 4 Different Pattern of Allelic Loss in Epstein-Barr Virus-Positive Gastric Cancer with Emphasis on the p53 Tumor Suppressor Pathway

CHAPTER 5 Epstein-Barr virus (EBV) in gastric carcinomas and gastric stump carcinomas: a late event in gastric carcinogenesis

CHAPTER 6 Cyclooxygenase-2 in Carcinogenesis of the Gastrointestinal Tract

CAHPTER 7 Expression of Cyclooxygenase-2 in Dysplasia of the Stomach and in Intestinal- type Gastric Adenocarcinoma

CHAPTER 8 Cyclooxygenase-2 expression during carcinogenesis in the human stomach

CHAPTER 9 Expression of Microsomal Prostaglandin E2 Synthase in Intestinal Type Gastric Adenocarcinoma and in Gastric Cancer Cell Lines

CHAPTER 10 Prognostic Significance of Elevated Cyclooxygenase 2 Expression in Patients With Adenocarcinoma of the Esophagus

CHAPTER 11 MOLECULAR EVIDENCE OF FIELD CANCERIZATION IN A PATIENT WITH 7 TUMORS OF THE AERODIGESTIVE TRACT

CHAPTER 12 Molecular Evidence for the Same Clonal Origin of Both Components of an Adenosquamous Barrett Carcinoma

CHAPTER 13 SUMMARY AND CONCLUDING REMARKS

CHAPTER 14 Samenvatting en Conclusies

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