The value of health-related quality of life assessment in cancer clinical trials

Thesis

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Titlepage

CONTENTS

CHAPTER 1 INTRODUCTION AND OUTLINE OF THE THESIS

CHAPTER 2 Health related quality of life in prostate carcinoma patients: a systematic review of randomized controlled trials

CHAPTER 3 Methodological issues in assessing health-related quality of life of colorectal cancer patients in randomised controlled trials

CHAPTER 4 Beyond the development of health-related quality of life (HRQOL) measures. A checklist for evaluating HRQOL outcomes in cancer clinical trials: does HRQOL evaluation in prostate cancer research inform clinical decision-making?

CHAPTER 5 Randomized, controlled trial investigating short-term health-related quality of life with doxorubicin and paclitaxel versus doxorubicin and cyclophosphamide as first-line chemotherapy in patients with metastatic breast cancer: European Organization for Research and Treatment of Cancer Breast Cancer Group; Investigational Drug Branch for Breast Cancer and the New Drug Development Group Study

CHAPTER 6 Baseline health-related quality of life data as prognostic factors in a phase III multicentre study of women with metastatic breast cancer

CHAPTER 7 Health-related quality of life parameters as prognostic factors in a non-metastatic breast cancer population: an international multicenter study

CHAPTER 8 SUMMARY AND GENERAL DISCUSSION

SAMENVATTING

Acknowledgements

Curriculum vitae

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