Control of functional T helper cell polarization by dendritic cells

Thesis

Cover

Titlepage

Abbreviations

Contents

CHAPTER 1 General Introduction

CHAPTER 2 Development of Th1-inducing Capacity in Myeloid Dendritic Cells Requires Environmental Instruction

CHAPTER 3 Microbial Compounds Selectively Induce Th1 Cell-promoting or Th2 Cell-promoting Dendritic Cells In Vitro with Diverse Th Cell-polarizing Signals

CHAPTER 4 ICOS-mediated Costimulation of Human T Helper Cells Promotes both Th1 and Th2 Cytokine Production but Selectively Promotes the Expansion of Th2 cells

CHAPTER 5 Prostaglandin E2 is a Selective Inducer of IL-12p40 Production and an Inhibitor of Bioactive IL-12p70 Heterodimer

CHAPTER 6 Glatiramer Acetate Promotes Th2 Cell Development and Increased IL-10 Production Through Modulation of Dendritic Cells

CHAPTER 7 Glucocorticoids Inhibit Bioactive IL-12p70 Production by In Vitro-Generated Human Dendritic Cells Without Affecting Their T cell Stimulatory Potential

CHAPTER 8 Glucocorticoids Transiently Inhibit the Maturation of Dendritic Cells but Permanentely Downregulate the IL-12 Production

CHAPTER 9 Dendritic Cells Interface Innate and Adaptive Immunity, General Discussion

APPENDICES

Summary

Nederlandse samenvatting

Acknowledgments

Curriculum vitae

Publications

Co-authors

Cover