Immediate total-body CT scanning after severe trauma

This thesis focuses on the consequences of immediate total-body CT (iTBCT) scanning in comparison to the standard work-up and the indication for iTBCT scanning after severe trauma in a large randomized controlled trial. Next to the effect on clinical outcomes, the effect on clinically relevant time intervals, radiation exposure and health economics effects are evaluated. These effects are also evaluated specifically for patients in need for emergency bleeding control interventions. The criteria for iTBCT are reconsidered in order to select the more severely injured patients and reduce the chance on unnecessary radiation exposure for the less severely injured patients.