Ligand denticity controls enantiomeric preference in DNA-based asymmetric catalysis
| Authors |
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| Publication date |
2012
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| Journal |
Chemical Communications
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| Volume | Issue number |
48 | 18
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| Pages (from-to) |
2394-2396
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| Organisations |
-
Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
|
| Abstract |
DNA-based catalysis can be used to control the enantioselectivity of copper-catalysed Diels-Alder and Friedel-Crafts reactions to produce either enantiomer of the product by changing the denticity of the ligand coordinated to the Cu(II) ion, even though the DNA adopts a right handed helical conformation only.
|
| Document type |
Article
|
| Language |
English
|
| Published at |
https://doi.org/10.1039/c2cc17350f
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