Dynamic control of VE-cadherin-based junctions

Authors	E. Timmerman
Supervisors	P.L. Hordijk
Cosupervisors	J.D. van Buul
Award date	03-07-2013
ISBN	9789461822833
Number of pages	164
Organisations	Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Cover Title pages Contents Chapter 1: General Introduction and scope of the thesis Chapter 2: Phosphorylation at endothelial cell-cell junctions: Implications for VE-cadherin function Chapter 3: The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation Chapter 4: Trio controls Rac1 activity to drive VE-cadherin-based junction formation and angiogenesis Addendum to chapter 4: Video 1A Addendum to chapter 4: Video 1B Addendum to chapter 4: Video 2 Addendum to chapter 4: Video 3 Chapter 5: Trio regulates a novel pro-inflammatory pathway through the transcription factor Ets2 Addendum to chapter 5: Video 1 Addendum to chapter 5: Video 2 Chapter 6: Plasminogen activator inhibitor-1 controls VE-cadherin-mediated endothelial cell-cell junctions Chapter 7: Summary and concluding remarks Nederlandse samenvatting Curriculum vitae List of publications Dankwoord
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