Remotely Controlled Iridium-Catalyzed Asymmetric Hydrogenation of Terminal 1,1-Diaryl Alkenes
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| Publication date | 19-08-2013 |
| Journal | Angewandte Chemie, International Edition |
| Volume | Issue number | 52 | 34 |
| Pages (from-to) | 8795-8797 |
| Number of pages | 3 |
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| Abstract | The presence of a remote directing group on terminal 1,1-diaryl and 1,1-dialkyl alkenes led to high and unprecedented enantioselectivity in iridium-catalyzed asymmetric hydrogenation (see scheme). This strategy offers efficient synthetic pathways towards valuable enantiomerically enriched 1,1-diaryl and 1,1-dialkyl alkanes. Moreover, the directing group can be further functionalized. |
| Document type | Article |
| Language | English |
| Related publication | Ferngesteuerte iridiumkatalysierte asymmetrische Hydrierung von terminalen 1,1‐Diarylalkenen |
| Published at | https://doi.org/10.1002/anie.201302942 https://doi.org/10.1002/ange.201302942 |
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