Human herpesvirus 8 and Kaposi's sarcoma in the Amsterdam cohort studies. Disease association, transmission and natural history

Thesis

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Titlepage

Table of Contents

1 Introduction

Part I Disease Association

2 Seroconversion for human herpesvirus 8 during HIV infection is highly predictive of Kaposi's sarcoma

Addendum Timing of Human Immunodeficiency Virus type 1 and Human Herpesvirus 8 Infections and length of the Kaposi's sarcoma-free period in coinfected persons

3 Clinical symptoms related to primary human herpesvirus 8 infection in homosexual men with or at risk for HIV-1 infection

4 Kaposi's sarcoma (KS) and human herpesvirus 8 (HHV8) infection do not protect HIV-1 infected homosexual men from AIDS dementia complex (ADC)

Part II Transmission

5 Risk factors for HHV8 seropositivity and HHV8 seroconversion in a cohort of homosexual men

6 Lack of evidence for blood-borne transmission of human herpesvirus 8 during 10 year follow-up (1985-1996) of drug users in the Netherlands

Part III Natural History

7 Two distinct gamma-2 herpesviruses in African green monkeys: a second gamma-2 herpesvirus lineage among old world primates?

8 Human herpesvirus 8 infections in the Amsterdam Cohort Studies (1984-1997): analysis of seroconversions to ORF65 and ORF73

9 VEGF levels in serum do not increase following HIV-1 and HHV8 seroconversion and lack correlation with AIDS-KS

10 General Discussion

Summary

Samenvatting

Curriculum Vitae

Dankwoord

Bibliography

STELLINGEN

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