C1-inhibitor potentiation by glycosaminoglycans

Authors	G.A.C. Bos
Supervisors	C.E. Hack J.P. Abrahams
Cosupervisors	E.F. Eldering
Award date	21-11-2003
ISBN	9090173862 9789090173863
Number of pages	144
Organisations	Faculty of Medicine (AMC-UvA)
Document type	PhD thesis
Note	Research conducted at: Immunologie
Language	English
Downloads	Thesis Cover Stellingen Titlepage CONTENTS Chapter 1 Introduction Chapter 2 Structural and functional aspects of C1-Inhibitor Chapter 3 The potentiation of human C1-Inhibitor by dextran sulphate is transient in vivo; studies in a rat model Chapter 4 Recombinant human C1-Inhibitor produced in Pichia pastoris has the same inhibitory capacity as plasma C1-Inhibitor Chapter 5 Effect of reactive site loop elongation on inhibitory activity of C1-Inhibitor Chapter 6 The functional integrity of the serpin domain of C1-Inhibitor depends on the unique N-terminal domain, as revealed by a pathological mutant Chapter 7 Potentiation mechanism of C1-Inhibitor differs from that of other serpins Chapter 8 Summarising Discussion Chapter 9 Samenvatting Chapter 10 Samenvatting voor niet-ingewijden Curriculum vitae & List of publications Dankwoord Cover
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