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  2. Control of cytotoxic responses on human neonates: naïvety or tight regulation?

Control of cytotoxic responses on human neonates: naïvety or tight regulation?

Open Access
Authors
  • L. do Ribeiro Couto
Supervisors
  • L.A. Aarden
Cosupervisors
  • C.J.P. Boog
Award date 04-07-2002
ISBN
  • 9090159339
  • 9789090159331
Number of pages 152
Organisations
  • Faculty of Medicine (AMC-UvA)
Document type PhD thesis
Note Research conducted at: Immunologie
Language English
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Thesis
Cover
Titlepage
Contents
Chapter 1 General Introduction
Chapter 2 Cytolytic Mechanisms and Expression of Activation-Regulating Receptors on Effector-Type CD8+CD45RA+CD27¯ Human T Cells
Chapter 3 High IL-13 Production by Human Neonatal T Cells: Neonate Immune System Regulator?
Chapter 4 Inhibition of potentially dangerous NK cell-mediated cytotoxicity by high expression of CD94/NKG2A on human neonatal NK cells
Chapter 5 Ultrastructural characterization of effector-target interactions for human neonatal and adult NK cells reveals reduced intercellular surface contacts of neonatal cells
Chapter 6 pDC2, B and T cell development in RAG2-/- γc-/- mice injected with unmanipulated cord blood CD34⁺ cells
Chapter 7 Lessons from human neonate cytotoxic lymphocytes: naive or (tightly) regulated? General Discussion
SUMMARY
Nederlandse Samenvatting
Abbreviations
Acknowledgements
CURRICULUM VITAE
PUBLICATIONS
ERRATUM
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