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  2. Synthesis of beta-carbolines as potential serotonine receptor ligands

Synthesis of beta-carbolines as potential serotonine receptor ligands

Open Access
Authors
  • B.E.A. Burm
Supervisors
  • G.J. Koomen
Cosupervisors
  • C.G. Kruse
Award date 13-01-1999
Organisations
  • Faculty of Science (FNWI) - Van 't Hoff Institute for Molecular Sciences (HIMS)
Document type PhD thesis
Note Research conducted at: IMC
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Thesis
Cover
Titlepages
Contents
Chapter 1: General introduction:5-Hydroxytryptamine receptors
Chapter 2: General introduction: Tetrahydro-ß-carbolines. Biosynthetic and synthetic approaches
Chapter 3: Synthesis of nazlinine analogues for 5-HT receptor affinity studies
Chapter 4: Enzymic and Biomimetic Oxidation Reactions of Nazlinine: Azepines and Indoloquinolizidines
Chapter 5: Ring closed analogues of nazlinine: (+)-Arborescidines A, B and C
Chapter 6: Bridged tetrahydro-ß-carbolines as conformationally restricted serotonine analogues
Chapter 7: Spiro-fused oxindoles as conformationally restricted serotonine and muscarine analogues
Chapter 8: Synthesis of Xestomanzamine A and B
Chapter 9: Receptor affinity studies
Summary
Samenvatting
Nawoord
Cover
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