Community-based studies on the epidemiology, treatment and prevention of malaria in an area of intense malaria transmission in western Kenya

Thesis

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Titlepage

Contents

Chapter 1 Introduction

Chapter 2 Protective effects of the sickle cell gene against malaria morbidity and mortality

Chapter 3 The relationship between the response to iron supplementation and sickle cell haemoglobin phenotype in pre-school children in western Kenya

Chapter 4 Increased efficacy of sulfadoxine-pyrimethamine in the treatment of uncomplicated falciparum malaria among children with sickle cell trait in western Kenya

Chapter 5 Treatment history and treatment dose are important determinants of sulfadoxine-pyrimethamine efficacy in children with uncomplicated malaria in western Kenya

Chapter 6 Sulfadoxine-pyrimethamine in treatment of malaria in western Kenya: increasing resistance and under-dosing

Chapter 7 Age-based antimalarial dosing: The use of weight-for-age reference data from malaria endemic countries to obtain safe and effective dose regimens

Chapter 8 Reduction of malaria during pregnancy by permethrin-treated bed nets in an area of intense perennial malaria transmission in western Kenya

Chapter 9 Impact of permethrin-treated bed nets on malaria, anaemia, and growth in infants in an area of intense perennial malaria transmission in western Kenya

Chapter 10 Impact of permethrin-treated bed nets on malaria and all-cause morbidity in young children in an area of intense perennial malaria transmission in western Kenya: cross-sectional survey

Chapter 11 Summary and discussion Samenvatting

Acknowledgments

Curriculum vitae

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