Modulation of human dendritic cell function by therapeutic agents

Thesis

Cover

Titlepage

Abbreviations

Contents

Chapter 1 General Introduction

Chapter 2 Granulocyte-macrophage colony-stimulating factor has opposing effects on the capacity of monocytes versus monocyte-derived dendritic cells to stimulate the antigen-specific proliferation of a human T cell clone

Chapter 3 Human immature dendritic cells efficiently bind and take up secretory IgA without the induction of maturation

Chapter 4 Phosphodiesterase 4 inhibitors reduce human dendritic cell inflammatory cytokine production and Th1-polarizing capacity

Chapter 5 Type I IFN differentially modulate IL-12p70 production by human dendritic cells depending on the maturation status of the cells and counteract IFN-γ-mediated signaling

Chapter 6 Glatiramer acetate (copolymer-1, Copaxone®) promotes Th2 cell development and increased IL-10 production through modulation of dendritic cells

Chapter 7 General Discussion

Summary

Samenvatting voor de niet-immunoloog

Dankwoord (dè bedankt zèt da witte)

Curriculum vitae

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