Apoptosis signaling to mitochondria by death receptors and DNA damaging anti-cancer regimens

Authors	A.B. Werner
Supervisors	J. Borst
Award date	10-06-2004
Number of pages	126
Organisations	Faculty of Science (FNWI) - Swammerdam Institute for Life Sciences (SILS)
Document type	PhD thesis
Note	Research conducted at: Universiteit van Amsterdam
Language	English
Downloads	Thesis (complete) Front cover Title pages TABLE OF CONTENTS Chapter 1 General Introduction Chapter 2 TRAIL receptor and CD95 signal to mitochondria via FADD, Caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid Chapter 3 Bcl-2 family member Bfl-1/A1 sequesters truncated Bid to inhibit its collaboration with pro-apoptotic Bak or Bax Chapter 4 Requirement for aspartate-cleaved Bid in apoptosis signaling by DNA damaging anti-cancer regimens Chapter 5 Mechanism of action for Drosophila Reaper in mammalian cells: Reaper globally inhibits protein synthesis and induces apoptosis independent of mitochondrial permeability Chapter 6 Summarizing Discussion Chapter 7 Nederlandse Samenvatting CURRICULUM VITAE LIST OF PUBLICATIONS DANKWOORD LIST OF ABBREVIATIONS
Permalink to this page

Back

UvA-DARE