Maxillomandibular advancement Issues related to indication, surgery, and outcome

Obstructive Sleep Apnea (OSA) is a common sleep-related breathing disorder that causes significant health problems. This condition is characterized by repeated episodes of partial or complete obstruction of the upper airway, leading to breathing disturbances and oxygen depletion. OSA affects sleep quality, cognitive function, and increases the risk of accidents. The prevalence of OSA is rising due to factors such as obesity and an aging population.
The diagnosis of OSA is often made through polysomnography, and treatment ranges from lifestyle adjustments to continuous positive airway pressure (CPAP) therapy. Maxillomandibular advancement (MMA) osteotomy, a form of orthognathic surgery, which involves adjusting the upper and lower jaws to enlarge the airway, is an effective surgical option.
This dissertation investigates various aspects of MMA for OSA. It assesses the clinical efficacy and safety of MMA in comparison to other surgical treatments. It identifies predictors of surgical success and evaluates the effectiveness of MMA in patients with different types of apnea. It also examines the suitability of MMA in patients with hypopnea-dominant OSA and the impact of MMA on the type of OSA.
Furthermore, an orthognathic treatment protocol for edentulous patients is examined, focusing on the accuracy and predictability without intraoperative wafers. The effect of surgical experience on the outcomes of MMA is also explored, as well as the surgical accuracy of performed MMA.
This thesis highlights MMA's role as an effective treatment option for OSA, with attention to patient selection, clinical efficiency, safety, and surgical accuracy. The results contribute to the understanding and development of MMA as a treatment for OSA.