Merging methodology & technology for light-mediated synthesis

Gone are the days when the development of new synthetic methods was the sole driving force in organic chemistry. Today, it's the convergence of groundbreaking methodologies and disruptive technology that is shaping the future of synthesis. Through this thesis, it was shown how that the future of light-mediated synthesis lies in the judicious combination of methodology and technology. In detail, the investigation conducted in this thesis involved employing hydrogen atom transfer (HAT), single-electron transfer (SET), and halogen atom transfer (XAT) activation pathways within the realm of photocatalysis. These methodologies were employed to advance diverse transformations, including amination, heteroarylation, trifluoromethoxylation, formation of C(sp³)−C(sp³) or C(sp³)‒C(sp²) bonds. To enhance efficiency, the integration of cutting-edge technologies such as 3D-printing, high-intensity light emitting diodes (LEDs), and continuous-flow systems was seamlessly woven into the synthesis methodologies.