On the use of antiretroviral medication for the treatment of HIV-1 infection in Thailand

Thesis

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Titlepage

Contents

Chapter 1 Introduction

Chapter 2 Pharmacokinetic study of saquinavir hard gel caps/ritonavir in HIV-1-infected patients: 1600/100 mg once daily compared with 2000/100 mg once daily and 1000/100 mg twice daily

Chapter 3 Interindividual variability of once daily ritonavir boosted saquinavir pharmacokinetics in Thai and UK patients

Chapter 4 Ketoconazole is inferior to ritonavir as an alternative booster for saquinavir in a once daily regimen in HIV-1 infected patients

Chapter 5 Nevirapine plasma concentrations and concomitant use of rifampin in patients coinfected with HIV-1 and tuberculosis

Chapter 6 Relationships between exposure to indinavir, efavirenz and ritonavir, and changes in fasted metabolic parameters and body fat distribution in HIV-infected patients switched to a nucleoside-analogue sparing regimen

Chapter 7 Study of the pharmaceutical and bioequivalence of the generic saquinavir in Thai healthy volunteers

Chapter 8 A pilot project for quality assessment and monitoring of generic antiretrovirals in Thailand

Chapter 9 Discussion

Summary/Samenvatting

Acknowledgements

Curriculum Vitae

Stellingen behorende bij het proefschrift

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