'Rapid speed of response to ECT in bipolar depression: A chart review
| Authors |
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|---|---|
| Publication date | 03-2022 |
| Journal | Journal of Psychiatric Research |
| Volume | Issue number | 147 |
| Pages (from-to) | 34-38 |
| Number of pages | 5 |
| Organisations |
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| Abstract |
Objective: To validate a faster speed of response to electroconvulsive therapy (ECT) for bipolar depression (BPD) compared to major depressive disorder (MDD) Method: Retrospective chart review on an ECT cohort in an academic hospital setting. Speed of response was defined by the number of ECT treatments needed for response or remission. Results: Sixty-four depressed patients were included, of whom 53 (MDD: 40, BPD: 13) could be analyzed. The bipolar group responded faster with a mean difference of 3.3 fewer ECT treatments to meet response criteria (MDD 10.4 vs. BPD 7.1, p = 0.054). When using mixed effects regression models for the response/remitter group (n = 35), a faster response for the bipolar group (AIC 252.83 vs 258.55, χ2 = 11.72, p = 0.008) was shown. Other factors, such as psychotic features or comorbidity, did not influence the speed of response. Conclusion: This chart review of an ECT cohort in an naturalistic academic hospital setting shows an evident and clinically relevant faster speed of response in bipolar depression. |
| Document type | Article |
| Note | With supplementary file |
| Language | English |
| Published at | https://doi.org/10.1016/j.jpsychires.2022.01.008 |
| Other links | https://www.scopus.com/pages/publications/85122474656 |
| Downloads |
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